Napoli left the Stadio Olimpico with a single point after Roma found an equaliser in stoppage time.
The Azzurri took the lead in the first half when Leonardo Spinazzola ran onto a ball played over the top and lobbed the onrushing keeper.
However, Angelino's volley two minutes into injury time earned the hosts a share of the spoils.
Roma 1-1 Napoli (1-0)
Scorers: Spinazzola 29, Angelino 90+2.
ROMA: Svilar; Rensch (Baldanzi 80), Mancini, N’Dicka, El Shaarawy (Saelemaekers 55), Pisilli, Cristante (Dovbyk 64), Kone (Paredes 56), Angelino, Soule, Shomurodov (Dybala 80).
Coach: Ranieri.
NAPOLI: Meret; Di Lorenzo, Rrahmani, Juan Jesus, Spinazzola, Anguissa, Lobotka, McTominay, Politano (Raspadori 86), Lukaku (Simeone 81), Neres (Mazzocchi 76).
Coach: Conte.
Referee: Fabbri (Ravenna).
Booked: Politano, Kone, Pisilli.